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Home - Department of Molecular Microbiology & Immunology

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Dr. Bill Wold, Chairman
Dr. Bill Wold, Chairman


Saint Louis University Medical Center | Edward A. Doisy Research Center

Rm 716 | 1100 South Grand | St. Louis, Missouri 63104
Phone 314.977.8850 Fax 314.977-8717 | Email: schwarda@slu.edu

Key Features

The Department has state-of-the-art laboratories located in a research and teaching complex together with other basic science departments in the School of Medicine.

The 11 primary and 16 secondary faculty in the Department have strong independent research programs funded by the government, research foundations, and industry. The faculty serve on national peer-review panels and journal editorial boards, are often invited to report on their work at other institutions, and their research is published in highly visible scientific journals. Students in the department receive progressive didactic instruction and extensive cutting-edge research training in virology, immunology, molecular biology, cell biology, cell-cell interactions.

 

Research in the Department of Molecular Microbiology and Immunology reflects the strength and diversity of its faculty through a unifying focus of the study of host-pathogen interactions, especially in the areas of virology and immunology.

    General areas of interest include:
  • viral pathogenesis
  • immunology
  • molecular and cellular biology
  • biodefense
    The virology program is one of the strongest in the USA, and it encompasses research on:
  • adenoviruses
  • hepatitis B and C viruses
  • Herpes simplex virus
  • HIV (structure-function of integrase enzyme)
  • poxviruses (including model studies for smallpox)
  • anti-viral drug therapy
  • cancer gene therapy using viral vectors
  • prions
    The immunology program includes research on:
  • immunotherapy of cancer
  • regulatory T cells in autoimmune disease
  • molecular mechanisms that control regulatory T cells
  • immunotherapy of chronic viral infection
  • osteoimmunology
  • cytokine function
  • vaccine development (discovery and clinical trials)
  • nutrophils and natural killer cells
    Other research:
  • parasites (T. cruzi)
  • Mycobacterium tuberculosis
  • cell cycle regulation
  • programmed cell death (apoptosis)
  • role of mitochondrial mutations in disease
  • ultrasensitive detection of nucleic acids and proteins

 

Dr. John Tavis
The Search Is On for a Hepatitis B Drug, Thanks to A Million Dollars in NIH Grants to SLU

Two grants from the National Institutes of Health will allow Saint Louis University researchers to build on breakthroughs in understanding the hepatitis B virus and begin the search for a drug to cure – not just halt – the illness.

Read More >>>

 



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