Richard J. Di Paolo, Ph.D.
Assistant Professor
Ph.D., Washington University, 1992
Email: rdipaolo@slu.edu
Phone: 314-977-6353
DiPaolo RJ, Brinster C, Davidson TS, Andersson J, Glass
D and Shevach EM
Autoantigen-Specific TGFbeta-Induced Foxp3+ Regulatory T
Cells Prevent Autoimmunity by Inhibiting Dendritic Cells
from Activating Autoreactive T Cells
J. Immunol. 2007 179:4685-4693.
Pubmed Abstract link: 17878367
Davidson TS, DiPaolo RJ, Andersson J, Shevach EM.
Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+
T
regulatory cells.
J Immunol. 2007 Apr 1;178(7):4022-6.
Pubmed Abstract link: 17371955
Zhao DM, Thornton AM, DiPaolo RJ, Shevach EM.
Activated CD4+CD25+ T cells selectively kill B lymphocytes.
Blood. 2006 May 15;107(10):3925-32.
Pubmed Abstract link: 16418326
DiPaolo RJ, Glass DD, Bijwaard KE, Shevach EM.
CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease
by
inhibiting the differentiation of autoreactive effector T cells.
J Immunol. 2005 Dec 1;175(11):7135-42.
Pubmed Abstract link: 16301616
Haeryfar SM, DiPaolo RJ, Tscharke DC, Bennink JR, Yewdell
JW.
Regulatory T cells suppress CD8+ T cell responses induced by direct priming
and
cross-priming and moderate immunodominance disparities.
J Immunol. 2005 Mar 15;174(6):3344-51.
Pubmed Abstract link: 15749866
Byersdorfer CA, Dipaolo RJ, Petzold SJ, Unanue ER.
Following immunization antigen becomes concentrated in a limited number of
APCs
including B cells.
J Immunol. 2004 Dec 1;173(11):6627-34.
Pubmed Abstract link: 15557153
DiPaolo RJ, Unanue ER.
Cutting edge: the relative distribution of T cells responding to chemically
dominant or minor epitopes of lysozyme is not affected by CD40-CD40 ligand
and
B7-CD28-CTLA-4 costimulatory pathways.
J Immunol. 2002 Sep 15;169(6):2832-6.
Pubmed Abstract link: 12218093
DiPaolo RJ, Unanue ER.
Cutting edge: chemical dominance does not relate to immunodominance: studies
of
the CD4+ T cell response to a model antigen.
J Immunol. 2002 Jul 1;169(1):1-4.
Pubmed Abstract link: 12077220
DiPaolo RJ, Unanue ER.
The level of peptide-MHC complex determines the susceptibility to autoimmune
diabetes: studies in HEL transgenic mice.
Eur J Immunol. 2001 Dec;31(12):3453-9.
Pubmed Abstract link: 11745364
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Cutting edge: a single MHC anchor residue alters the conformation of a
peptide-MHC complex inducing T cells that survive negative selection.
J Immunol. 2001 May 15;166(10):5874-7.
Pubmed Abstract link: 11342600
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Quantitative analysis of the T cell repertoire that escapes negative selection.
Immunity. 1999 Oct;11(4):453-62.
Pubmed Abstract link: 10549627
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Cutting edge: negative selection of immature thymocytes by a few peptide-MHC
complexes: differential sensitivity of immature and mature T cells.
J Immunol. 1999 Mar 15;162(6):3117-20.
Pubmed Abstract link: 10092759