Richard J. Di Paolo, Ph.D. Recent Publications
Shevach EM, Davidson TS, DiPaolo RJ, Andersson J.
Role of TGF-beta in the induction of FoxP3 expression and T regulatory cell function.
J. Clin. Immunol. 2008 Sept. 23 accepted for publication.
Stummvoll GH, DiPaolo RJ, Huter EN, Davidson TS, Glass D, Ward JM, Shevach EM.
Th1, th2, and th17 effector T cell-induced autoimmune gastritis differs in
pathological pattern and in susceptibility to suppression by regulatory T cells.
J Immunol. 2008 Aug 1;181(3):1908-16.
Pubmed Abstract link: 18641328
DiPaolo RJ, Brinster C, Davidson TS, Andersson J, Glass D and Shevach EM
Autoantigen-Specific TGFbeta-Induced Foxp3+ Regulatory T
Cells Prevent Autoimmunity by Inhibiting Dendritic Cells
from Activating Autoreactive T Cells
J. Immunol. 2007 179:4685-4693.
Pubmed Abstract link: 17878367
Davidson TS, DiPaolo RJ, Andersson J, Shevach EM.
Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T
regulatory cells.
J Immunol. 2007 Apr 1;178(7):4022-6.
Pubmed Abstract link: 17371955
Zhao DM, Thornton AM, DiPaolo RJ, Shevach EM.
Activated CD4+CD25+ T cells selectively kill B lymphocytes.
Blood. 2006 May 15;107(10):3925-32.
Pubmed Abstract link: 16418326
DiPaolo RJ, Glass DD, Bijwaard KE, Shevach EM.
CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by
inhibiting the differentiation of autoreactive effector T cells.
J Immunol. 2005 Dec 1;175(11):7135-42.
Pubmed Abstract link: 16301616
Haeryfar SM, DiPaolo RJ, Tscharke DC, Bennink JR, Yewdell JW.
Regulatory T cells suppress CD8+ T cell responses induced by direct priming and
cross-priming and moderate immunodominance disparities.
J Immunol. 2005 Mar 15;174(6):3344-51.
Pubmed Abstract link: 15749866
Byersdorfer CA, Dipaolo RJ, Petzold SJ, Unanue ER.
Following immunization antigen becomes concentrated in a limited number of APCs
including B cells.
J Immunol. 2004 Dec 1;173(11):6627-34.
Pubmed Abstract link: 15557153
DiPaolo RJ, Unanue ER.
Cutting edge: the relative distribution of T cells responding to chemically
dominant or minor epitopes of lysozyme is not affected by CD40-CD40 ligand and
B7-CD28-CTLA-4 costimulatory pathways.
J Immunol. 2002 Sep 15;169(6):2832-6.
Pubmed Abstract link: 12218093
DiPaolo RJ, Unanue ER.
Cutting edge: chemical dominance does not relate to immunodominance: studies of
the CD4+ T cell response to a model antigen.
J Immunol. 2002 Jul 1;169(1):1-4.
Pubmed Abstract link: 12077220
DiPaolo RJ, Unanue ER.
The level of peptide-MHC complex determines the susceptibility to autoimmune
diabetes: studies in HEL transgenic mice.
Eur J Immunol. 2001 Dec;31(12):3453-9.
Pubmed Abstract link: 11745364
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Cutting edge: a single MHC anchor residue alters the conformation of a
peptide-MHC complex inducing T cells that survive negative selection.
J Immunol. 2001 May 15;166(10):5874-7.
Pubmed Abstract link: 11342600
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Quantitative analysis of the T cell repertoire that escapes negative selection.
Immunity. 1999 Oct;11(4):453-62.
Pubmed Abstract link: 10549627
Peterson DA, DiPaolo RJ, Kanagawa O, Unanue ER.
Cutting edge: negative selection of immature thymocytes by a few peptide-MHC
complexes: differential sensitivity of immature and mature T cells.
J Immunol. 1999 Mar 15;162(6):3117-20.
Pubmed Abstract link: 10092759
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