Dubec SJ, Aurora R, Zassenhaus HP.
Mitochondrial DNA mutations may contribute to aging via cell death caused by peptides that induce cytochrome c release.
Rejuvenation Res. 2008 Jun;11(3):611-9.
Pubmed Abstract Link: 18593279

Bensch KG, Degraaf W, Hansen PA, Zassenhaus HP, Corbett JA.
A transgenic model to study the pathogenesis of somatic mtDNA mutation accumulation in beta-cells.
Diabetes Obes Metab. 2007 Nov;9 Suppl 2:74-80.
Pubmed Abstract Link: 17919181

Mott JL, Zhang D, Chang SW, Zassenhaus HP.
Mitochondrial DNA mutations cause resistance to opening of the permeability
transition pore.
Biochim Biophys Acta. 2006 May-Jun;1757(5-6):596-603.
Pubmed Abstract link: 16829230

Mott JL, Zhang D, Zassenhaus HP.
Mitochondrial DNA mutations, apoptosis, and the misfolded protein response.
Rejuvenation Res. 2005 Winter;8(4):216-26.
Pubmed Abstract link: 16313221

Zhang D, Mott JL, Chang SW, Stevens M, Mikolajczak P, Zassenhaus HP.
Mitochondrial DNA mutations activate programmed cell survival in the mouse heart.
Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2476-83.
Pubmed Abstract link: 15840907

Zhang D, Ezekiel UR, Chang SW, Zassenhaus HP.
Gene expression profile in dilated cardiomyopathy caused by elevated frequencies of mitochondrial DNA mutations in the mouse heart.
Cardiovasc Pathol. 2005 Mar-Apr;14(2):61-9.
Pubmed Abstract link: 15780797

Mott JL, Zhang D, Freeman JC, Mikolajczak P, Chang SW, Zassenhaus HP.
Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A.
Biochem Biophys Res Commun. 2004 Jul 9;319(4):1210-5.

Zhang D, Mott JL, Farrar P, Ryerse JS, Chang SW, Stevens M, Denniger G, Zassenhaus HP.
Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy. Cardiovasc Res. 2003 Jan;57(1):147-57.

Mott JL, Zhang D, Stevens M, Chang S, Denniger G, Zassenhaus HP.
Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations.
Mutat Res. 2001 Mar 1;474(1-2):35-45.

Mott JL, Denniger G, Zullo SJ, Zassenhaus HP.
Genomic structure of murine mitochondrial DNA polymerase-gamma.
DNA Cell Biol. 2000 Oct;19(10):601-5.

Zhang D, Mott JL, Chang SW, Denniger G, Feng Z, Zassenhaus HP.
Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis.
Genomics. 2000 Oct 15;69(2):151-61.

Li H, Zassenhaus HP.
Phosphorylation is required for high-affinity binding of DBP, a yeast mitochondrial site-specific RNA binding protein.
Curr Genet. 2000 Jun;37(6):356-63.

Chang SW, Zhang D, Chung HD, Zassenhaus HP.
The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain.
Biochem Biophys Res Commun. 2000 Jun 24;273(1):203-8.

Mott JL, Zhang D, Farrar PL, Chang SW, Zassenhaus HP.
Low frequencies of mitochondrial DNA mutations cause cardiac disease in the mouse.
Ann N Y Acad Sci. 1999;353-7.
Li H, Zassenhaus HP.
Purification and characterization of an RNA dodecamer sequence binding protein from mitochondria of Saccharomyces cerevisiae.
Biochem Biophys Res Commun. 1999 Aug 11;261(3):740-5.

Margossian SP, Li H, Zassenhaus HP. and Butow RA.
The DExH box protein Suv3p is a component of a yeast mitochondrial 3'-to-5' exoribonuclease that suppresses group I intron toxicity.
Cell. 1996 Jan 26;84(2):199-209.

Ezekiel UR, Towler EM, Wallis JW, Zassenhaus HP.
Evidence for a nucleotide-dependent topoisomerase activity from yeast mitochondria.
Curr Genet. 1994 Dec;27(1):31-7.

Ezekiel UR, Zassenhaus HP.
Evidence for a site-specific endonuclease in yeast mitochondria which recognizes the sequence 5'GCCGGC.
Biochem Biophys Res Commun. 1994 May 30;201(1):208-14.

Zassenhaus HP. and Denniger G.
Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination.
Curr Genet. 1994 Feb;25(2):142-9.

Hofmann TJ, Min J, Zassenhaus HP.
Formation of the 3' end of yeast mitochondrial mRNAs occurs by site-specific cleavage two bases downstream of a conserved dodecamer sequence.
Yeast. 1993 Dec;9(12):1319-30.

Min J, Zassenhaus HP.
A nucleoside triphosphate-regulated, 3' exonucleolytic mechanism is involved in turnover of yeast mitochondrial RNAs.
J Bacteriol. 1993 Oct;175(19):6245-53.

Ezekiel UR, Zassenhaus HP.
Localization of a cruciform cutting endonuclease to yeast mitochondria.
Mol Gen Genet. 1993 Sep;240(3):414-8.

Min J, Zassenhaus HP.
Identification of a protein complex that binds to a dodecamer sequence found at the 3' ends of yeast mitochondrial mRNAs.
Mol Cell Biol. 1993 Jul;13(7):4167-73.

Min J, Heuertz RM, Zassenhaus HP.
Isolation and characterization of an NTP-dependent 3'-exoribonuclease from mitochondria of Saccharomyces cerevisiae.
J Biol Chem. 1993 Apr 5;268(10):7350-7.