Daniel S. Zahm, Ph.D.
 | Professor Previously: Professor (1995-2004), Department of Anatomy and Neurobiology, Saint Louis University School of Medicine; Research Associate (1982-1985), Departments of Neurology, Neurosurgery and Otolaryngology, University of Virginia School of Medicine, Charlottesville, VA Pennsylvania State University, 1982 Phone: (314)977-8003 zahmds@slu.edu |
Research Summary
The laboratory seeks to understand fundamental patterns of organization in the basal forebrain, how forebrain systems contribute to behavioral synthesis and brain development and what the vulnerabilities of different forebrain systems are in circumstances leading to neurodegeneration.
Honors and Awards
Leverhulme Visiting Professorship, University of St. Andrews, St. Andrews, Scotland, June-December, 2000
Forbairt Visiting Professorship, Royal College of Surgeons and Trinity College, Dublin, June - July, 1997
Grant Support
USPHS-NIH/NS-23805 (R01)
Convergent vs. Parallel Striatal Afferents
9/1/1988-11/30/2012
Professional Memberships
Editorial Boards: Neuroscience (1995-present); Journal of Comparative Neurology (2004-2007); Journal of Chemical Neuroanatomy (2005-present); Brain Structure and Function (2006-present)
Society for Neuroscience
International Brain Research Organization
Faculty Appointments
Professor
Department of Pharmacological and Physiological Science
Saint Louis University School of Medicine
Previously: Professor (1995-2004), Department of Anatomy and Neurobiology, Saint Louis University School of Medicine; Research Associate (1982-1985), Departments of Neurology, Neurosurgery and Otolaryngology, University of Virginia School of Medicine, Charlottesville, VA
Teaching Experience
Current Research Activities
Publications
Selected Papers from 90:
Zahm, D.S., Pharmacological approach to the treatment of addiction: persisting challenges. Missouri Medicine 107:276-280, 2010.
Zahm, D.S., Becker M.L., Freiman A.J., Strauch S., DeGarmo B., Geisler S., Meredith G.E., and Marinelli M.: Fos after single and repeated self-administration of cocaine and saline in the rat: emphasis on the basal forebrain and recalibration of expression. Neuropsychopharmacology, 35:445-463, 2010 (at 8/20/10, cited 1 time).
Jhou, TC., Geisler, S., Marinelli, M., and Zahm, D.S.: Medial tegmental nucleus: a mesopontine structure targeted by the lateral habenula that projects to the ventral tegmental area and substantia nigra compacta. J . Comp. Neurol. 513:566-596, 2009 (at 8/20/10 cited 11 times).
Geisler, S., Marinelli, M., DeGarmo, B., Becker M.L., Freiman, A.J., Beales, M., Meredith, G.E., and D.S. Zahm: Prominent activation of brainstem and pallidal afferents of the ventral tegmental area by cocaine. Neuropsychopharmacology, 33:2688-2700, 2008 (at 8/20/10, cited 9 times).
Zahm, D.S.: The dopaminergic projection system, basal forebrain macrosystems, and conditioned stimuli. CNS Spectrums 13:887-892, 2008 (at 9/10/09 cited 3 times).
Geisler, S., Derst, C., Veh, R.W. and D.S. Zahm: Glutamatergic afferents of the ventral tegmental area in the rat. J. Neurosci. 27:5730-5743, 2007 (at 8/21/10, cited 61 times).
Zahm, D.S. The evolving theory of basal forebrain "functional anatomical macrosystems. Neurosci. Biobehav. Rev., 30:148-172, 2006 (at 8/20/10, cited 30 times).
Reynolds, S.M., and D.S. Zahm: Macrosystem-specificity of projections from prefrontal and insular cortex to ventral striatopallidum and extended amygdala. J. Neurosci. 25:11757-11767, 2005 (at 8/20/10, cited 35 times).
Geisler, S., and D.S. Zahm: Afferents of the ventral tegmental area in the rat - anatomical substratum for integrative functions. J. Comp. Neurol. 490:270-294, 2005 (at 8/20/10 cited 75 times).
Zahm, D.S.: An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbens. Neurosci. Biobehav. Rev. 24:85-105, 2000 (at 8/20/10, cited 210 times).
Brog, J.S., A. Salypongse, A.Y. Deutch and D.S. Zahm: The patterns of afferent innervation of the core and shell in the "accumbens" part of the rat ventral striatum: Immunohistochemical detection of retrogradely transported Fluoro-Gold. J. Comp. Neurol., 338:255-278, 1993 (at 8/20/10, cited 514 times).
Zahm, D.S. and J.S. Brog: Commentary: On the significance of the core-shell boundary in the rat nucleus accumbens. Neuroscience 50:751-767, 1992 (at 8/20/10, cited 641 times).
Zahm, D.S.: Accumbens in a Functional-Anatomical Systes Context: In: (David H, ed.) The nucleus accumbens: neurotransmitters and related behaviours, Transworld Research Network-Research Signpost, Kerala, India, pgs. 1-37, 2008.
Zahm, D.S., and L. Heimer: Limbic System. In: (Binder MD, Hirokawa N and Windhorst U, eds.) Encyclopedia of Neuroscience, Vol. 3 H-M, Springer, pgs. 2157-2161, 2009.
Heimer, L., Van Hoesen, G.W., Trimble, M., Zahm, D.S. Anatomy of Neuropsychiatry. The New Anatomy of the Basal Forebrain and its Implications for Neuropsychiatric Illness. Elsevier, Amsterdam. 2008.
Dopamine-containing neurons
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