Lauren Stein, a graduate student in the Yosten/Samson lab, received her doctorate at the SLU 2016 Graduate Programs commencement exercises May 12th. In April Dr. Stein received the Research Recognition Award from the Endocrinology and Metabolism Section of the American Physiological Society for her work identifying the receptor of the novel peptide hormone, Phoenixin, which was discovered by Drs. Yosten and Samson in 2013.

Dr. Stein has accepted an NIH funded postdoctoral fellowship in the Department of Psychiatry and the Translational Neurosciences Program at the Perlman School of Medicine, University of Pennsylvania. Dr. Stein will be continuing her studies on  the neuroendocrinology of energy balance in the laboratory of Dr. Matthew Hayes.
Willis K. Samson Ph.D. D.Sc. has been elected by the membership of the American Physiological Society to serve on its governing Council. Click here to read more.

Contact Us
Department of Pharmacological and Physiology
Room M 362 || 1402 South Grand Blvd
St. Louis, Missouri 63104
Phone: 314-977-6400
Fax: 314-977-6410

Primary Faculty Appointments

NameDegree InstitutionAcademic Interest
Alan H. Stephenson, Ph.D.
Saint Louis University, 1986

Vascular control mechanisms: eicosanoids, pulmonary & cardiovascular science.

Amy Harkins, Ph.D.
Department of Biomedical Engineering,
Saint Louis University
(secondary appointment)
University of Pennsylvania, 1993

Cellular and molecular mechanisms of synaptic vesicle release; calcium channels.

Andrew A. Butler, Ph.D

University of Auckland 
Auckland, New Zealand (1995)

Neural “nutrient sensing networks” control ingestive behaviors and metabolism to maintain metabolic homeostasis and a healthy body weight.

Andrew Lechner, Ph.D.
University of California, Riverside, 1977

Pulmonary physiology; acute lung injury and the immunophysiology of sepsis.

Colin A. Flaveny Ph.D.
Doctor of Philosophy 
Molecular Toxicology 08/04-05/10
The Pennsylvania State University 
University Park PA
Pharmacological targeting of LXR to treat prostate cancer
Daniel S. Zahm, Ph.D.
Pennsylvania State University, 1982

Neuroanatomical and functional organization of basal forebrain; neurodegeneration, role of peptides in psychostimulant and opioid actions.

Daniela Salvemini, Ph.D.
University of London, 1990

Role of reactive oxygen and nitrogen  species and lipid mediators in acute and chronic pain and in the development of opiate antinociceptive tolerance.

Gina Yosten, Ph.D.
Ph.D., Saint Louis University

Role of Orphan GPCRs in Obesity- and Diabetes-Associated Cardiovascular Disease

Heather Macarthur, Ph.D.
William Harvey Research Institute 
Saint Bartholomew's Medical College
London, 1994

Vascular control mechanisms; endothelial mediators; sympathetic neurotransmission.

Jane Cox, Ph.D.
Ireland (Dublin), 1983

Neurotransmitter receptors; molecular biology and developmental regulation of glutamate and P2X receptors.

Jinsong Zhang, Ph.D.

Ph.D., University of Pennsylvania (1999)

Transcriptional regulation in animal cells
John C. Chrivia, Ph.D.
University of Washington, 1987

Transcriptional reegulation by coactivators and nuclear receptors.

John K. Walker, Ph.D.
Ph.D. 1998
Indiana University 
Bloomington, IN
Medicinal Chemistry and Drug Design

Research Interests: Our laboratory is focused on the application of medicinal and synthetic organic chemistry toward the development of potential new therapeutic agents. We rely on structure based drug design and ligand based drug design techniques as well traditional medicinal chemistry principles to design these new molecules. Our research is highly collaborative and we are engaged in projects with a number of groups looking at new drug targets for anti-inflammatory, anti-bacterial and anti-caner agents.

Joseph Baldassare, Ph.D.
MIT and University of Pittsburgh, 1971

Cell-cycle regulation and intracellular signal transduction mechanisms.

Mark M. Knuepfer, Ph.D.
Iowa, 1981

Autonomic pharmacology and physiology; central cardiovascular regulation; electrophysiology; effects of cocaine, stress and endotoxemia.

Mark M. Voigt, Ph.D.
Saint Louis University, 1985

Biochemical and molecular neuropharmcology and neuroscience; molecular biology and development regulation of purinergic receptors; development of sensory neurons in zeberafish.

Michael Ariel, Ph.D.
Washington University, 1980

Sensorimotor information processing from visual and vestibular inputs that control eye movements.

Randy S. Sprague, M.D.
Saint Louis University, 1976

The role of the red blood cell as a determinant of vascular resistance.

Terrance M. Egan, Ph.D.
M.I.T., 1984

Receptor and voltage gated ion channels.

Thomas P. Burris, Ph.D.
Ph.D., The Florida State University
Thomas C. Westfall, Ph.D.
West Virginia, 1962

William Beaumont Professor, Chair Emeritus
Biochemical neuropharmacology; monoamine and peptide regulation; autonomic pharmacology and cardiovascular science.

W. Michael Panneton, Ph.D.
The Ohio State University, 1978

The etiology of Parkinson disease; neural pathways mediating deep chronic pain; neural integration of somatautonomic reflexes (the diving response).

Willis K. Samson, Ph.D., D.Sc.
University of Texas, 1979

Neuropeptides and the control of cardiovascular function and stress hormone secretion